National Level Online Quiz On Thyroid In Pathology Diagnosis

 

An 18-year-old female presents with a painless 1cm mass in the anterior neck region. A biopsy is taken revealing fluid contained within pseudostratified columnar epithelium.What is the most likely diagnosis? 

Branchial cyst

Thyroglossal duct cyst

Answer: Thyroglossal duct cyst

 

Which of the following features are NOT consistent with anaplastic carcinoma? 

Occasional osteoclast-like multinucleated giant cells

Positive thyroglobulin markers

Answer: Positive thyroglobulin markers

 

Which of the following features is NOT typical for Graves disease? 

Infiltration of mononuclear cells into retro-orbital connective tissues

Extensive infiltration of the mononuclear cells into the thyroid parenchyma

Answer: Extensive infiltration of the mononuclear cells into the thyroid parenchyma

 

What thyroid cancer has the worst prognosis? (choose the answer that shows the correct descending order, the first being the cancer with the worst prognosis and the last being the one with the best prognosis) 

anaplastic > medullary > follicular > papillary

medullary > anaplastic > papillary > follicular

Answer: anaplastic > medullary > follicular > papillary

 

A 28-year-old man presents to his GP with a 4cm mobile anterior neck mass. A fine needle aspirate is performed which reveals cells with ‘orphan Annie eye’ nuclei and psammoma bodies. What is the most likely diagnosis? 

Thyroglossal duct cyst

Papillary carcinoma

Answer: Papillary carcinoma

 

A 62-year-old gentleman presents to the clinic with a 5cm painless neck mass as well as diarrhoea for the past 3 months. A biopsy is taken and he is subsequently diagnosed with medullary carcinoma.Which of the following features is consistent with a medullary carcinoma? 

Dense fibrosis of the thyroid gland

Formation of microabscesses

Answer: Dense fibrosis of the thyroid gland

 

Which of the following features is NOT consistent with follicular carcinoma? 

Follicular carcinomas are diagnosed via fine needle aspiration

More common in women than men

Answer: Follicular carcinomas are diagnosed via fine needle aspiration

 

A 37-year-old woman presents to the clinic with 2 days of sudden onset pain in the anterior neck radiating to the jaw. She is otherwise well having reported a full recovery from a ‘cold’ a week ago. What findings are NOT consistent with her diagnosis? 

Dense fibrosis of the thyroid gland

Formation of microabscesses

Answer: Dense fibrosis of the thyroid gland

 

A 46-year-old female presents to the preadmission clinic and is found to have a 3cm anterolateral firm painless neck mass along with a minor decrease in calcium serum levels.What is the most likely diagnosis? 

Follicular carcinoma

Papillary carcinoma

Medullary carcinoma

Answer: Medullary carcinoma

 

What is the most common type of thyroid carcinoma? 

Medullary carcinoma

Papillary carcinoma

Answer: Papillary carcinoma